Amid growing calls for larger allocations of monkeypox vaccine, Los Angeles County this week received less than half the number of doses it originally anticipated, health officials said Wednesday, but it will still begin offering second doses of the two-shot regimen to those eligible for it.
According to the county Department of Public Health, the county had anticipated receiving 14,000 vials of vaccine, enough to administer 70,000 shots. But the federal government notified the county this week it would actually only be receiving 5,600 vials, enough to administer 28,000 doses.
“Public Health has received assurances from the federal leadership that additional doses will be available in the coming weeks,” according to a statement from the agency.
Despite the smaller-than-anticipated allocation, the county will still begin offering second doses of the vaccine to roughly 8,000 people eligible to receive them. The second doses will be available to people who received their first dose at least 28 days ago, with the shots available either through a personal health care provider or through the county’s registration system, if they received the initial dose from the county. Another 19,000 doses from the weekly allocation will be distributed to community providers and public vaccination sites to be used as first doses. In addition, 1,000 doses will be reserved for close contacts of existing patients, for outbreak control and special populations at high risk of infection.
The county this week transitioned to a newly approved method of administering smaller doses of the monkeypox vaccine, a move that led to a five- fold increase in the availability of shots locally. The U.S. Food and Drug Administration last week allowed the JYNNEOS vaccine to be administered between layers of skin, in what’s called an intradermal injection. Previously, the vaccine was administered beneath the skin, in a subcutaneous injection. The intradermal method requires only roughly one-fifth the amount of vaccine required by the subcutaneous injection, authorities said.
Making the change is designed to stretch the limited of supply of the vaccine nationally, allowing smaller doses to be administered to more people. The county has simplified its previously complex system for determining who is eligible to receive a monkeypox vaccine. The shots are now available to any gay or bisexual man or transgender person age 18 and older who has had multiple or anonymous sex partners in the previous 14 days. People who were eligible under the county’s previous guidelines will remain eligible for the shots.
The previous guidelines made shots available to people confirmed by the Department of Public Health to have had high- or immediate-risk contact with a known monkeypox patient, and to people who attended an event or visited a venue where there was a high risk of exposure to a confirmed case.
Shots were also available for gay and bisexual men and transgender people with a diagnosis of rectal gonorrhea or early syphilis within the past year. Also eligible for the shots are gay or bisexual men or transgender people who are on HIV pre-exposure prophylaxix, or PrEP, or who attended or worked at a commercial sex venue or other venue where they had anonymous sex or sex with multiple partners — such as at a sauna, bathhouse or sex club — in the past 21 days.
Residents who fall into the eligibility criteria can register online at ph.lacounty.gov/monkeypoxsignup to be alerted when a vaccine dose is available.
As of Wednesday, Aug. 17, the county has identified a total of 993 confirmed or probably cases of monkeypox, up from 738 last Thursday. Almost all of the cases are in men, the majority of them gay or bisexual.
Monkeypox is generally spread through intimate skin-to-skin contact, resulting from infectious rashes and scabs, though respiratory secretions and bodily fluids exchanged during extended physical episodes, such as sexual intercourse, can also lead to transmission, according to the U.S. Centers for Disease Control. It can also be transmitted through the sharing of items such as bedding and towels. Symptoms include fresh pimples, blisters, rashes, fever and fatigue. There is no specific treatment. People who have been infected with smallpox, or have been vaccinated for it, may have immunity to monkeypox.
According to health officials, the vaccine can prevent infection if given before or shortly after exposure to the virus. More information is available online at ph.lacounty.gov/monkeypox.